I noticed this is an old thread from August, so the OP might not actually be reading responses....
That said, I had issues running at non-standard resolutions on some older builds of BII -- it wouldn't crash, but the emulation would slow to a crawl. Recent versions for OS X and Windows don't seem to exhibit this problem though.
Make sure you're giving the emulator enough memory.
Also, it seems to me that driving a Performa at 4K resolution would be a bit unproductive - have you tried scaling 1024x768 instead?
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